Home » Groups


The SynCogDys network is formed by 10 research groups from universities and research institutes across Spain. These cover all major fields of expertise in neuroscience: behavioural research in animal models, functional studies on behaving animals, synaptic physiology, pharmacology, cell biology, neuronal circuits, optogenetics, biochemistry, molecular biology and computational biology. While using different methodological approaches all these groups share an interest in the biology of synapses, both in health and disease.

List of all Research Groups

Cellular Biology of the Synapse

Isabel Pérez Otaño , Ph.D. | Instituto de Neurociencias, CSIC-Universidad Miguel Hernández ( Sant Joan d'Alacant (Spain) )

A fundamental question in neuroscience is how neuronal circuits are refined by environmental cues. Circuit refinements involve maturation of selected synaptic connections and elimination (“pruning”) of others and are most prominent during [...]

Continue reading »

Division of Neurosciences, Pablo de Olavide University

Agnès Gruart Massó , Ph.D. | Universidad Pablo de Olavide ( Sevilla (Spain) )

Our group has been devoted to the study of the neurophysiological basis of animal behavior, from the generation of simple motor responses to the neuronal control of complex behaviors. Our experimental approach is both comparative and [...]

Continue reading »

Laboratorio de Circuitos Neuronales

Liset M de la Prida , Ph.D. | Instituto Cajal - CSIC ( Madrid (Spain) )

The main goal of the Menéndez de la Prida's lab is to understand the function of the hippocampal and para-hippocampal circuits in the normal and the epileptic brain. We are interested on how complex patterns of activity are produced with a special [...]

Continue reading »

Molecular and cellular mechanisms for synaptic plasticity

José A. Esteban , Ph.D. | Centro de Biología Molecular Severo Ochoa ( Madrid (Spain) )

My research group has a longstanding interest in the molecular and cellular mechanisms of synaptic plasticity, and their contribution to cognitive processes such as learning and memory. Using electrophysiological, imaging and molecular techniques, [...]

Continue reading »

Molecular Basis of Memory

Carlos Sindreu , Ph.D. | University of Barcelona (Spain) ( Barcelona )

The central nervous system has the remarkable ability to process and store information. A crucial step in the formation of long-term memory (LTM) is consolidation, a process in which short-term memory (STM) is converted to LTM. Another striking [...]

Continue reading »

Molecular Physiology of the Synapse

Àlex Bayés , Ph.D. | Institut de investigació Biomèdica Sant Pau ( Barcelona (Spain) )

Our research aims to understand the molecular mechanisms governing synaptic function. We are specially interested in the proteomic study of postsynaptic protein complexes found at glutamatergic synapses, particularly the postsynaptic density, as [...]

Continue reading »

Neurobiology of ionotropic Glutamate receptors in health and disease

Xavier Altafaj , Ph.D. | Institut d’investigació Biomèdica Bellvitge ( Barcelona (Spain) )

The iGluRsNeuroLab aims to understand the physiology of NMDA-type ionotropic glutamate receptors (iGluRs) and to unveil the molecular and cellular mechanisms bridging the gap between glutamate receptor dysfunctions and neurological diseases, towards [...]

Continue reading »

Neurogenetics and Synaptopathies

Francisco Manuel Gomez Scholl , Ph.D. | Universidad de Sevilla (Spain) ( Sevilla )

Our research is focused on the study of the mechanisms that regulate synapse formation and function in normal conditions and their role in the onset of brain disorders, particularly autism and Alzheimer’s [...]

Continue reading »

Synaptic Physiology

Juan Lerma , Ph.D. | Instituto de Neurociencias de Alicante ( San Juan de Alicante (Spain) )

Glutamate acts as a neurotransmitter at most excitatory synapses and is involved in long-lasting plastic phenomena as well as in neuronal dead-associated pathology such as neurodegeneration. During previous projects, our group have characterized and [...]

Continue reading »

Transcriptional and Epigenetic Mechanisms of Neuronal Plasticity

Angel Barco , Ph.D. | Instituto de Neurociencias de Alicante ( San Juan de Alicante (Spain) )

We are interested in the molecular mechanisms underlying learning and memory storage, more precisely in the role of transcriptional and epigenetic processes in neuronal plasticity. We also investigate how the malfunction of these mechanisms may lead [...]

Continue reading »