Groups

A fundamental question in neuroscience is how neuronal circuits are refined by environmental cues. Circuit refinements involve maturation of selected synaptic connections and elimination (“pruning”) of others and are most prominent during [...]

Our group has been devoted to the study of the neurophysiological basis of animal behavior, from the generation of simple motor responses to the neuronal control of complex behaviors. Our experimental approach is both comparative and [...]

The main goal of the Menéndez de la Prida's lab is to understand the function of the hippocampal and para-hippocampal circuits in the normal and the epileptic brain. We are interested on how complex patterns of activity are produced with a special [...]

My research group has a longstanding interest in the molecular and cellular mechanisms of synaptic plasticity, and their contribution to cognitive processes such as learning and memory. Using electrophysiological, imaging and molecular techniques, [...]

The central nervous system has the remarkable ability to process and store information. A crucial step in the formation of long-term memory (LTM) is consolidation, a process in which short-term memory (STM) is converted to LTM. Another striking [...]

Our research aims to understand the molecular mechanisms governing synaptic function. We are specially interested in the proteomic study of postsynaptic protein complexes found at glutamatergic synapses, particularly the postsynaptic density, as [...]

The iGluRsNeuroLab aims to understand the physiology of NMDA-type ionotropic glutamate receptors (iGluRs) and to unveil the molecular and cellular mechanisms bridging the gap between glutamate receptor dysfunctions and neurological diseases, towards [...]

Our research is focused on the study of the mechanisms that regulate synapse formation and function in normal conditions and their role in the onset of brain disorders, particularly autism and Alzheimer’s [...]

Glutamate acts as a neurotransmitter at most excitatory synapses and is involved in long-lasting plastic phenomena as well as in neuronal dead-associated pathology such as neurodegeneration. During previous projects, our group have characterized and [...]

We are interested in the molecular mechanisms underlying learning and memory storage, more precisely in the role of transcriptional and epigenetic processes in neuronal plasticity. We also investigate how the malfunction of these mechanisms may lead [...]