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Experimental induction of trans-synaptic long-term potentiation

Since the early 70’s of the past century, long-term potentiation (LTP) evoked experimentally by high-frequency stimulation (HFS) protocols is a popular technique for the study of cellular and molecular mechanisms underlying learning-dependent changes in synaptic strength. It was described for the first time in the hippocampus of anesthetized rabbits, but these seminal studies were followed […]

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